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Prevent Delirium

Empowering Hospitals
with Technology, Support and Data-Driven Decision Making


More than 20% of patients aged over 60 suffer from postoperative delirium (POD) after surgery. Symptoms include disorientation, memory loss, difficulty in speech, and behavioural changes. Delirium is often preventable by non-pharmacological interventions for those at risk.

Delirium Leads To

6x Nursing home admissions
14x Risk of dementia

7.4m EUR Average annual cost per hospital

Average length of stay increased by 3 days

Identify Patients with PIPRA

PIPRA has created the richest database in the market on POD, which is used to train our algorithm. Our CE-certified software is designed to fit into the clinical pathway with a simple to use interface that runs in the background once integrated, delivering an immediate stratification of risk.

  • Secure web solution
  • High performance
  • No device required
  • CE-marked
  • Pay-per-use
  • No installation required
  • Flexible integration (0-100%)
  • Patient data protected
  • Delirium prevention support bundle included
  • Fully integrated into your IT landscape

PIPRA explained

Algorithm Development and Roll-Out Options
Development & Validation Process
Roll-out option 1
Roll-out option 2

Revolutionizing Patient Care

Better POD Prevention

PIPRA’s score-based risk assessment helps clinicians to better personalise their patient’s operative plan and to decrease the risk of developing POD.

  • Lower Delirium incidence
  • Reduced length of stay
  • Reduced nursing hours
  • Improved risk assessment
  • Improved Coding

POD tackling Strategy &  Transformation support

Through training, informative materials, and on-the-ground support, care staff gains practical guidance to effectively manage delirium. This enables them to enhance their skills, improve patient care and experience the benefits of streamlined workflows.

POD Performance Insights

Continuous data-backed insights and feedback into daily delirium practices empowers hospitals to swiftly adapt their delirium management plan. PIPRA's robust data analytics capabilities further enhance hospitals' ability to make informed, data-driven decisions, streamline operations and ultimately optimize their financial performance.

Collaborate with us






Medically Approved in EU (CE-certified)

Medically approved & reimbursed in:

  • Switzerland
  • Austria
  • Finland
  • Ireland
  • Germany
  • Belgium
  • Sweden
  • Portugal
  • France
  • The Netherlands
  • Spain
  • Estonia


"There is a perception that elective surgeries have become extremely safe, thanks to advances in operative technique and anesthesia care. This view overlooks the fact that a substantial number of patients, in particular older ones, experience adverse cognitive outcomes after surgery. PIPRA has a game-changing solution which squarely addresses this need. It estimates delirium risk accurately and reliably, thanks to an AI algorithm trained on routinely collected clinical data. This is an extraordinarily valuable tool which will have a positive impact on choices made by patients undergoing surgery and their families, as well as surgeons, anesthesiologists, nurses, and other professionals who have a stake in the perioperative enterprise.”

Robert D Stevens, MD, MBA, FCCM
Johns Hopkins University
Director Division of Informatics and Precision Medicine (Prec. Med.), Co-director Prec. Med. Center of Excellence in Neurocritical Care, Head Lab. of Computational Intensive Care Med., Department of Anesthesiology & Critical Care Med., Secondary appointments in Biomedical & Electrical & Computer Engineering

“As clinicians consider and discuss surgical risks for their patients, we should similarly consider the risk for post-operative delirium. The use of PIPRA can personalize this risk calculation and provide both patients and clinicians with actionable information, with the purpose of instituting a delirium mitigation plan for that specific individual."

José R. Maldonado, M.D., FACLP, FACFE
Stanford University School of Medicine
John & Terry Levin Family Professor of Medicine
Professor of Psychiatry and, by courtesy, of Internal Medicine, Surgery,
Emergency Medicine & Law Chief, Division of Medical Psychiatry

“PIPRA proposes a new tool that allows rapid determination of an individual patients risk to develop postoperative delirium after an operation. This is a very exciting and important development which can improve current clinical practice. We will finally be able to not only target resource intensive non-pharmacological preventive interventions to those patients who benefit the most but we will also be able to design clinical trials regarding delirium based on risk groups."

Prof. Dr. med. Luzius Steiner
Head of Anaesthesiology, Universitätsspital Basel

"PIPRA is a huge advancement compared to the usual standard of care. The score that distinguishes between those at risk and those who are not is tremendously helpful."

Dr. med. Henry Perschak
Former Head of the International Medical Center, Klinik Hirslanden Zurich

“In case of surgery, we all expect to recover fully and fast. The reality is often different. PIPRA is applying cutting edge technology to make surgery for all of us safer. PIPRA is a great idea with a great team to make it happen."

Dr. Jürg Wittwer
CEO Touring Club Schweiz

“Patients who develop delirium while in hospital cause a disproportionately high additional workload for nurses. This quickly becomes a vicious cycle. The less time nurses have for a patient, the higher the likelihood that the patient will develop delirium. PIPRA identifies patients who are at risk and thereby enables nurses to initiate and control the relevantclinical care process in a timely and targeted manner. Early intervention through PIPRA can prevent delirium, and decrease workload and stress fornurses. This is an important contribution to healthcare providers, considering the current high volume of work and the problem of scarce personnel resources in the field of nursing."

Martin Zozmann
Pflegeexperte/ Nursing Research Coordinator, Klinik Hirslanden

Our Publications

Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery
An Individual Patient Data Meta-Analysis
Behnam Sadeghirad, PharmD, MPH, PhD; Benjamin T. Dodsworth, DPhil; Nayeli Schmutz Gelsomino, MD; Nicolai Goettel, MD; Jessica Spence, MD, PhD; Tayler A. Buchan, MSc; Holly N. Crandon, BHSc
JAMA Netw Open. 2023;6(10):e2337239. doi:10.1001/jamanetworkopen.2023.37239
Development and validation of an international preoperative risk assessment model for postoperative delirium
Benjamin T. Dodsworth, Kelly Reeve, Lisa Falco, Tom Hueting, Behnam Sadeghirad, Lawrence Mbuagbaw, Nicolai Goettel, Nayeli Schmutz Gelsomino
Age and Ageing, Volume 52, Issue 6, June 2023, afad086, Published: 08 June 2023 https://doi.org/10.1093/ageing/afad086

Want to contact us?

PIPRA AG has developed a cutting-edge AI-based pre-operative risk assessment tool called PIPRA (short for Pre-Interventional Preventive Risk Assessment), to assess the risk of a patient developing POD. The test uses standard medical data, is web-or app-based, and takes less than two minutes to provide a score-based risk assessment. This risk assessment enables doctors, nurses and health services to better personalise their patient’s operative plan and to introduce key clinical interventions to reduce the patient’s risk of developing POD.