Collaborate with us

We are looking for Research Partners!

We are seeking partnerships to develop and apply new digital health technologies to delirium.

Would you like to join PIPRA's journal club?

We meet regularly to critically discuss recent publications about delirium. If you're interested, send an email to our Chief Scientific Officer, Dr. Benjamin Dodsworth,

Delirium Hub powered by PIPRA

PIPRA has created the Delirium Hub, an online platform designed to empower healthcare professionals (nurses, clinicians, but also students) worldwide in the prevention and management of delirium. Our mission is clear: to ensure everyone has access to vital knowledge about delirium, saves time, reduces stress, and fosters confidence in tackling even the most challenging cases. That's why, we decided to make it accessible free of charge for everyone.

  • Accessible Knowledge: Our goal is to make delirium education available to all, regardless of location or resources.
  • Time-Saving: We help to streamline daily delirium prevention and management tasks, alleviating the burden on healthcare professionals.
  • Empowerment: We aim to empower healthcare professionals to confidently manage delirium.

As of today, no precise tool for patient screening and risk determination is yet available in the current clinical practice.​

Preventive strategies could help reduce POD incidence and thus improve patient’s quality of life.  For instance, finding the high-risk patients preoperatively would allow for the adoption of tailored and protective perioperative measures.
In parallel, it would also be crucial to properly inform patients about their risk of suffering from cognitive impairment after undergoing any surgery, under general anesthesia.

The impact of post-operative delirium on patients is enormous.

Dr. med. Rebecca von Haken from the University Hospital Mannheim and member of the Delir Network, Heidelberg has much experience with patients who end up with POD. What impact has a post-operative delirium in older people? And what are she and her team doing to help patients with a high risk of post-operative delirium?

Interesting Articles

Our Publications:
Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac SurgeryAn Individual Patient Data Meta-Analysis
JAMA Netw Open. 2023;6(10):e2337239. doi:10.1001/jamanetworkopen.2023.37239
Development and validation of an international preoperative risk assessment model for postoperative delirium
Benjamin T. Dodsworth, Kelly Reeve, Lisa Falco, Tom Hueting, Behnam Sadeghirad, Lawrence Mbuagbaw, Nicolai Goettel, Nayeli Schmutz Gelsomino
Exploratory Budget Impact Analysis of a Preoperative Risk Assessment for Postoperative Delirium
Kempers, J.
This paper explores the expected impact of implementation of the PIPRA tool on hospital budget.
Preoperative prognostic factors associated with postoperative delirium in older people undergoing surgery: protocol for a systematic review and individual patient data meta-analysis.
Buchan, T.A., Sadeghirad, B., Schmutz, N. et al. Syst Rev 9, 261 (2020). doi: 10.1186/s13643-020-01518-z.
Consequences of Delirium:
Figure: consequences of delirium

13.9x new dementia diagnosis after adjusting for baseline characteristics
70% of cases not diagnosed
Cochrane Reviews:
Interventions for preventing delirium in hospitalised non ICU patients
Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients: (43% reduction in incidence)
Societies recommending pre-operative identification of high-risk patientss:
European Society of Anaesthesiology evidence-based and consensus-based guidelines on postoperative delirium
American Society of Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention
American Geriatrics Society
American Society of Anaesthesiology: Postoperative Brain Health initiative
Australian Society for Geriatric Medicine